Hi @Faheem, try this script. It will let your instances be accessed from port 80 and 22.
import boto3
from botocore.exceptions import ClientError
ec2 = boto3.client('ec2')
response = ec2.describe_vpcs()
vpc_id = response.get('Vpcs', [{}])[0].get('VpcId', '')
try:
    response = ec2.create_security_group(GroupName='SECURITY_GROUP_NAME',
                                         Description='DESCRIPTION',
                                         VpcId=vpc_id)
    security_group_id = response['GroupId']
    print('Security Group Created %s in vpc %s.' % (security_group_id, vpc_id))
    data = ec2.authorize_security_group_ingress(
        GroupId=security_group_id,
        IpPermissions=[
            {'IpProtocol': 'tcp',
             'FromPort': 80,
             'ToPort': 80,
             'IpRanges': [{'CidrIp': '0.0.0.0/0'}]},
            {'IpProtocol': 'tcp',
             'FromPort': 22,
             'ToPort': 22,
             'IpRanges': [{'CidrIp': '0.0.0.0/0'}]}
        ])
    print('Ingress Successfully Set %s' % data)
except ClientError as e:
    print(e)